Tianjin Perennial Hospital Immune Disease Medical Center: Overview and Specialized Clinical Programs

I. Center Overview

The Tianjin Perennial Hospital Immune Disease Medical Center (Department of Rheumatology and Immunology) is the first medical center in Tianjin with immunology as its core specialty. It was officially established and began clinical operations on January 1, 2026. The center is built around the core concept of "immune assessment, intervention, and reconstitution," and is dedicated to establishing a comprehensive immunology platform bridging basic research and clinical application, advancing precision diagnosis and treatment, as well as research translation for immune-related diseases.

The center comprises three major platforms: the Immune Disease Ward, the Immune Disease Specialty Clinic, and the Clinical Research Center for Immune Homeostasis and Healthy Longevity. Its clinical and research scope covers autoimmune diseases, immunodeficiency disorders, allergic diseases, immune exhaustion disorders, onco-immunology, neuroimmunological diseases, and aging-related conditions. Leveraging advanced diagnostic technologies (such as age-stratified immune assessment, thymic function evaluation, and autoimmune disease immune profiling) and innovative therapies (including immune modulation, antibody therapy, cell therapy, and immune reconstitution), the center provides comprehensive, life-cycle-oriented, and personalized diagnostic and treatment services.

II. Expert Team

The director of the center is Dr. Zhu Jiaxin, MD, who trained under Professor Li Zhanguo at the Clinical Immunology Center/Rheumatology and Immunology Department of Peking University People's Hospital. Dr. Zhu leads a multidisciplinary team with expertise in rheumatology and immunology, nephrology, pulmonology, neurology, gastroenterology, endocrinology, traditional Chinese medicine, immunology, and genetics. The center maintains close collaborations with renowned institutions, including the Rheumatology and Immunology Specialty Alliance of Peking University People's Hospital, the Department of Immunology at Peking University Health Science Center, and Tan Tock Seng Hospital in Singapore, ensuring that its clinical practice remains aligned with international standards.

III. Specialized Clinical Programs

The center offers a multi-tiered, multi-dimensional system of clinical programs tailored to patient needs, encompassing basic services, conventional treatments, high-value services, and cutting-edge therapies. Details are as follows:

Basic Clinical Services:

·Intra-articular injection therapy for osteoarthritis

·Ultrasound-mediated transdermal drug delivery for osteoarthritis and lumbar spine pain

·Osteoporosis screening and treatment

·Integrated traditional Chinese and Western medicine treatment for gout and metabolic regulation

·Autoimmune disease screening

Conventional Programs (Standardized Diagnosis and Treatment):

·Specific diagnostic and novel immunotherapeutic approaches for rheumatic and immunologic diseases

·Biologic and systemic therapy for various arthritides (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, etc.)

·Standardized and biologic therapy for systemic lupus erythematosus, Sjögren's syndrome, vasculitis, and other autoimmune conditions

·Early diagnosis and comprehensive treatment of osteoporosis, osteoarthritis, and soft tissue rheumatism

Innovative Programs (Precision Medicine):

·Assays for characteristic autoantibodies, cytokines, pharmacogenetic guidance, and pathogenic genotyping in autoimmune diseases

·Systemic immunoadsorption therapy

·Novel biologic therapies

·Surgical removal of gouty tophi combined with integrated traditional Chinese and Western medicine therapy

·Comprehensive surgical management of joint damage in rheumatic diseases (e.g., synovial hypertrophy, spinal deformities)

·Gut microbiome analysis and fecal microbiota transplantation

·Multidisciplinary diagnosis and standardized treatment of rare diseases (e.g., Behçet's disease, IgG4-related disease, SAPHO syndrome)

High-Tech Programs (Cutting-Edge Exploration):

·Comprehensive systemic immunomodulatory therapy for rheumatoid arthritis, systemic lupus erythematosus, and other autoimmune diseases

·Targeted B-cell immune clearance and immune reconstitution therapy

·Personalized immune reconstitution strategies for systemic immune diseases

IV. Center Vision

The center targets major clinical challenges such as "same cause with different outcomes, same disease with different manifestations, same treatment with different responses," and is committed to advancing the precise and personalized diagnosis and treatment of immune diseases. It aims to build an innovation chain for immune-based medicine, contributing to the development of immunology in Tianjin and across China.